Detalhe da pesquisa
1.
Dose selection for aztreonam-avibactam, including adjustments for renal impairment, for Phase IIa and Phase III evaluation.
Eur J Clin Pharmacol
; 80(4): 529-543, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38252170
2.
Pharmacodynamics of Meropenem and Tobramycin for Neonatal Meningoencephalitis: Novel Approaches to Facilitate the Development of New Agents to Address the Challenge of Antimicrobial Resistance.
Antimicrob Agents Chemother
; 66(4): e0218121, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35315689
3.
Flomoxef and fosfomycin in combination for the treatment of neonatal sepsis in the setting of highly prevalent antimicrobial resistance.
J Antimicrob Chemother
; 77(5): 1334-1343, 2022 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35170719
4.
Assessment of flomoxef combined with amikacin in a hollow-fibre infection model for the treatment of neonatal sepsis in low- and middle-income healthcare settings.
J Antimicrob Chemother
; 77(12): 3349-3357, 2022 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36177766
5.
Amikacin Combined with Fosfomycin for Treatment of Neonatal Sepsis in the Setting of Highly Prevalent Antimicrobial Resistance.
Antimicrob Agents Chemother
; 65(7): e0029321, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33972238
6.
Considerations in the Selection of Renal Dosage Adjustments for Patients with Serious Infections and Lessons Learned from the Development of Ceftazidime-Avibactam.
Antimicrob Agents Chemother
; 64(4)2020 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32015049
7.
Pharmacodynamics of the Novel Metallo-ß-Lactamase Inhibitor ANT2681 in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae.
Antimicrob Agents Chemother
; 64(11)2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32778549
8.
Pharmacodynamics of Cefepime Combined with the Novel Extended-Spectrum-ß-Lactamase (ESBL) Inhibitor Enmetazobactam for Murine Pneumonia Caused by ESBL-Producing Klebsiella pneumoniae.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32253209
9.
Intrapulmonary Pharmacokinetics of Cefepime and Enmetazobactam in Healthy Volunteers: Towards New Treatments for Nosocomial Pneumonia.
Antimicrob Agents Chemother
; 65(1)2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33077666
10.
Selecting the dosage of ceftazidime-avibactam in the perfect storm of nosocomial pneumonia.
Eur J Clin Pharmacol
; 76(3): 349-361, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31836928
11.
Pharmacodynamics of Tebipenem: New Options for Oral Treatment of Multidrug-Resistant Gram-Negative Infections.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31109982
12.
Dose Selection and Validation for Ceftazidime-Avibactam in Adults with Complicated Intra-abdominal Infections, Complicated Urinary Tract Infections, and Nosocomial Pneumonia.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30670413
13.
Ceftaroline fosamil doses and breakpoints for Staphylococcus aureus in complicated skin and soft tissue infections.
J Antimicrob Chemother
; 74(2): 425-431, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30380060
14.
Avibactam Pharmacokinetic/Pharmacodynamic Targets.
Antimicrob Agents Chemother
; 62(6)2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29610208
15.
Ceftazidime-Avibactam Susceptibility Breakpoints against Enterobacteriaceae and Pseudomonas aeruginosa.
Antimicrob Agents Chemother
; 62(11)2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30061279
16.
Reply to Asempa et al., "The Ongoing Challenge with NDM-Harboring Enterobacteriaceae in Murine Infection Models".
Antimicrob Agents Chemother
; 65(2)2021 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33229430
17.
Phase I Study Assessing the Pharmacokinetic Profile, Safety, and Tolerability of a Single Dose of Ceftazidime-Avibactam in Hospitalized Pediatric Patients.
Antimicrob Agents Chemother
; 60(10): 6252-9, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27503642
18.
Phase 1 study assessing the steady-state concentration of ceftazidime and avibactam in plasma and epithelial lining fluid following two dosing regimens.
J Antimicrob Chemother
; 70(10): 2862-9, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26133566
19.
Phase I study assessing the safety, tolerability, and pharmacokinetics of avibactam and ceftazidime-avibactam in healthy Japanese volunteers.
J Infect Chemother
; 21(8): 551-8, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26076867
20.
Assessment of the mass balance recovery and metabolite profile of avibactam in humans and in vitro drug-drug interaction potential.
Drug Metab Dispos
; 42(5): 932-42, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24616266